Deficiencies in traditional measures of in vitro hippocampal rhythms

Gillis, J. A., Zhang, L., Skinner, F. K. (2006) Deficiencies in traditional measures of in vitro hippocampal rhythms. Neurocomputing, 69 (10-12). pp. 1385-1390. ISSN 09252312 (ISSN)

URL: http://www.sciencedirect.com/science/article/pii/S...
DOI: 10.1016/j.neucom.2005.12.112

Abstract

An in vitro thick slice mouse hippocampus preparation exhibits spontaneous rhythmic local field potentials in the 3-4 Hz range due to synchronous discharges in the inhibitory interneuron population. Intracellular rhythms are recorded concurrently with field rhythms from this preparation in data sets of approximately 3 min durations. Cross-correlation, phase and frequency distribution are used to compare intracellular and field rhythms and generate groups of activity in the time-frequency domain. We find that patterns of activity present in time-frequency are obscured using other techniques and we characterize the activity that is omitted. © 2006 Elsevier B.V. All rights reserved.

Item Type: Paper
Uncontrolled Keywords: Cross-correlation EEG Intracellular Spontaneous Time-frequency Brain Cells Electroencephalography Mathematical models Neural networks Intracellular rhythms Spontaneous rhythmic local field potentials Time-frequency domain Neurology animal tissue article correlation coefficient electroencephalogram hippocampus in vitro study interneuron mouse nerve cell membrane potential newborn nonhuman priority journal rat signal processing time
Subjects: Investigative techniques and equipment
organs, tissues, organelles, cell types and functions > tissues types and functions > hippocampus
organs, tissues, organelles, cell types and functions > tissues types and functions
CSHL Authors:
Communities: CSHL labs > Gillis Lab
Depositing User: Matt Covey
Date Deposited: 04 Apr 2013 13:36
Last Modified: 04 Apr 2013 13:36
URI: http://repository.cshl.edu/id/eprint/28076

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