[One decade of functional imaging in schizophrenia research. From visualisation of basic information processing steps to molecular-genetic oriented imaging]

Tost, H., Meyer-Lindenberg, A., Ruf, M., Demirakca, T., Grimm, O., Henn, F. A., Ende, G. (February 2005) [One decade of functional imaging in schizophrenia research. From visualisation of basic information processing steps to molecular-genetic oriented imaging]. Radiologe, 45 (2). 113-8, 120. ISSN 0033-832X (Print)0033-832X (Linking)

URL: http://www.ncbi.nlm.nih.gov/pubmed/15742098
DOI: 10.1007/s00117-004-1154-1

Abstract

Modern neuroimaging techniques such as magnetic resonance imaging (MRI) and positron emission tomography (PET) have contributed tremendously to our current understanding of psychiatric disorders in the context of functional, biochemical and microstructural alterations of the brain. Since the mid-nineties, functional MRI has provided major insights into the neurobiological correlates of signs and symptoms in schizophrenia. The current paper reviews important fMRI studies of the past decade in the domains of motor, visual, auditory, attentional and working memory function. Special emphasis is given to new methodological approaches, such as the visualisation of medication effects and the functional characterisation of risk genes.

Item Type: Paper
Uncontrolled Keywords: Biological Markers/metabolism Brain/ pathology/ physiopathology Brain Mapping/ methods Clinical Trials as Topic Gene Expression Profiling/methods Humans Magnetic Resonance Imaging/ methods/trends Molecular Biology/ methods Research Design Risk Assessment/ methods Risk Factors Schizophrenia/ diagnosis/genetics/metabolism
Subjects: Investigative techniques and equipment
Investigative techniques and equipment > magnetic resonance imaging
CSHL Authors:
Communities: CSHL labs > Henn lab
Depositing User: Matt Covey
Date: February 2005
Date Deposited: 01 Mar 2013 21:52
Last Modified: 01 Mar 2013 21:52
Related URLs:
URI: http://repository.cshl.edu/id/eprint/27676

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