Criteria for annotation of plant MicroRNAs

Meyers, B. C., Axtell, M. J., Bartel, B., Bartel, D. P., Baulcombe, D., Bowman, J. L., Cao, X., Carrington, J. C., Chen, X., Green, P. J., Griffiths-Jones, S., Jacobsen, S. E., Mallory, A. C., Martienssen, R. A., Poethig, R. S., Qi, Y., Vaucheret, H., Voinnet, O., Watanabe, Y., Weigel, D., Zhu, J. K. (December 2008) Criteria for annotation of plant MicroRNAs. The Plant cell, 20 (12). pp. 3186-90. ISSN 1040-4651 (Print)1040-4651 (Linking)

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URL: http://www.ncbi.nlm.nih.gov/pubmed/19074682
DOI: 10.1105/tpc.108.064311

Abstract

MicroRNAs (miRNAs) are approximately 21 nucleotide noncoding RNAs produced by Dicer-catalyzed excision from stem-loop precursors. Many plant miRNAs play critical roles in development, nutrient homeostasis, abiotic stress responses, and pathogen responses via interactions with specific target mRNAs. miRNAs are not the only Dicer-derived small RNAs produced by plants: A substantial amount of the total small RNA abundance and an overwhelming amount of small RNA sequence diversity is contributed by distinct classes of 21- to 24-nucleotide short interfering RNAs. This fact, coupled with the rapidly increasing rate of plant small RNA discovery, demands an increased rigor in miRNA annotations. Herein, we update the specific criteria required for the annotation of plant miRNAs, including experimental and computational data, as well as refinements to standard nomenclature.

Item Type: Paper
Uncontrolled Keywords: Computational Biology MicroRNAs/*genetics RNA, Plant/*genetics RNA, Small Interfering/genetics Sequence Analysis, RNA
Subjects: organism description > plant > Arabidopsis
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification
bioinformatics > genomics and proteomics > genetics & nucleic acid processing
bioinformatics > genomics and proteomics
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > miRNA
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > miRNA

organism description > plant
CSHL Authors:
Communities: CSHL labs > Martienssen lab
Depositing User: Matt Covey
Date: December 2008
Date Deposited: 28 Feb 2013 15:26
Last Modified: 28 Feb 2013 15:26
PMCID: PMC2630443
Related URLs:
URI: http://repository.cshl.edu/id/eprint/27508

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