Eating to exit: autophagy-enabled senescence revealed

White, E., Lowe, S. W. (April 2009) Eating to exit: autophagy-enabled senescence revealed. Genes Dev, 23 (7). pp. 784-787. ISSN 0890-9369

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URL: http://www.ncbi.nlm.nih.gov/pubmed/19339684
DOI: 10.1101/gad.1795309

Abstract

Autophagy and senescence are two distinct cellular responses to stress that are also tumor suppression mechanisms. In this issue of Genes & Development, Young and colleagues ( pp. 798-803) discovered that autophagy is induced during and facilitates the process of senescence. Knowing now that these two pathways are functionally intertwined sets the stage for establishing how they function cooperatively in the cancer setting.

Item Type: Paper
Uncontrolled Keywords: Senescence autophagy oncogene ONCOGENE-INDUCED SENESCENCE CELLULAR SENESCENCE METABOLIC STRESS MICE TUMORIGENESIS SUPPRESSION CANCER APOPTOSIS SURVIVAL DISEASE
Subjects: organs, tissues, organelles, cell types and functions > cell types and functions > cell functions
organs, tissues, organelles, cell types and functions > cell types and functions
organs, tissues, organelles, cell types and functions > cell types and functions > cell functions > senescence
CSHL Authors:
Communities: CSHL labs > Lowe lab
Depositing User: Matt Covey
Date: April 2009
Date Deposited: 21 Feb 2013 17:51
Last Modified: 03 Nov 2017 20:13
Related URLs:
URI: http://repository.cshl.edu/id/eprint/27365

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