Sundaramurthy, P., Sreenivasan, R., Shameer, K., Gakkhar, S., Sowdhamini, R. (February 2011) Poster: HORIBALFRE: Higher order residue interactions based ALgorithm for fold REcognition. 1st International Conference onComputational Advances in Bio and Medical Sciences (ICCABS). p. 262.
Abstract
In an attempt to enhance the potential based fold - recognition methods of remote homologs, we propose a new approach "Higher Order Residue Interaction Based ALgorithm for Fold REcognition (HORIBALFRE)", where we incorporated the potential contributions not just from one-body and two-body terms, but from three body (triplet interactions) and four-body (quadruple interaction) interactions, to implement a new fold recognition method. Core of HORIBALFRE includes the potentials generated from a structure library derived from CAMPASS database of structure based sequence alignment. Currently, the algorithm is applied to the Fischer's dataset. Our preliminary result indicates that inclusion of higher order residue interaction (quadruple) potentials increases the prediction performance. © 2011 IEEE.
| Item Type: | Paper |
|---|---|
| Additional Information: | Meeting Abstract |
| Subjects: | bioinformatics bioinformatics > computational biology Publication Type > Meeting Abstract |
| CSHL Authors: | |
| Communities: | CSHL labs > McCombie lab |
| Depositing User: | Matt Covey |
| Date: | February 2011 |
| Date Deposited: | 05 Feb 2013 16:44 |
| Last Modified: | 28 Feb 2018 16:39 |
| URI: | https://repository.cshl.edu/id/eprint/27208 |
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