Oscillations and sparsening of odor representations in the mushroom body

Perez-Orive, J., Mazor, O., Turner, G. C., Cassenaer, S., Wilson, R. I., Laurent, G. (2002) Oscillations and sparsening of odor representations in the mushroom body. Science, 297 (5580). pp. 359-365. ISSN 00368075 (ISSN)

URL: http://www.ncbi.nlm.nih.gov/pubmed/12130775
DOI: 10.1126/science.1070502

Abstract

In the insect olfactory system, oscillatory synchronization is functionally relevant and reflects the coherent activation of dynamic neural assemblies. We examined the role of such oscillatory synchronization in information transfer between networks in this system. The antennal lobe is the obligatory relay for olfactory afferent signals and generates oscillatory output. The mushroom body is responsible for formation and retrieval of olfactory and other memories. The format of odor representations differs significantly across these structures. Whereas representations are dense, dynamic, and seemingly redundant in the antennal lobe, they are sparse and carried by more selective neurons in the mushroom body. This transformation relies on a combination of oscillatory dynamics and intrinsic and circuit properties that act together to selectively filter and synthesize the output from the antennal lobe. These results provide direct support for the functional relevance of correlation codes and shed some light on the role of oscillatory synchronization in sensory networks.

Item Type: Paper
Uncontrolled Keywords: Neural networks Odors Oscillations Synchronization Sensory networks Neurology insect odor oscillation animal anatomy animal experiment antennal lobe article controlled study correlation function information processing memory mushroom body nerve cell network neurotransmission nonhuman olfactory nervous system priority journal sensory nerve cell signal processing smelling Action Potentials Animals Electric Stimulation Electrodes Evoked Potentials Excitatory Postsynaptic Potentials Female gamma-Aminobutyric Acid Grasshoppers Interneurons Male Mushroom Bodies Nerve Net Neural Inhibition Neurons Patch-Clamp Techniques Picrotoxin Smell Synaptic Transmission Time Factors Animalia Basidiomycota Insecta
Subjects: organism description > animal > insect
organs, tissues, organelles, cell types and functions > tissues types and functions > mushroom body
organs, tissues, organelles, cell types and functions > tissues types and functions > neural networks
organs, tissues, organelles, cell types and functions > cell types and functions > cell types > neurons
organs, tissues, organelles, cell types and functions > cell types and functions > cell types > neurons
organs, tissues, organelles, cell types and functions > cell types and functions > cell types > neurons

organism description > animal behavior > olfactory
CSHL Authors:
Communities: CSHL labs > Turner lab
Depositing User: CSHL Librarian
Date Deposited: 11 Apr 2012 14:29
Last Modified: 14 Mar 2013 16:16
Related URLs:
URI: http://repository.cshl.edu/id/eprint/26141

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