Human ROS1 and MAS1 oncogenes located in regions of chromosome 6 associated with tumor-specific rearrangements

Rabin, M., Birnbaum, D., Young, D., Birchmeier, C., Wigler, M. H., Ruddle, F. H. (July 1987) Human ROS1 and MAS1 oncogenes located in regions of chromosome 6 associated with tumor-specific rearrangements. Oncogene Res, 1 (2). pp. 169-78. ISSN 0890-6467 (Print)

URL: https://www.ncbi.nlm.nih.gov/pubmed/3329713

Abstract

Oncogenes have been implicated in tumorigenesis based on their localization to chromosomal sites associated with tumor-specific structural rearrangements. We have mapped the human ros1 (formerly mcf3) and mas1 oncogenes to the distal half of chromosome 6q, within a region frequently rearranged in malignant cells. Chromosomal mapping of these two new human transforming genes may help elucidate the involvement of the long arm of chromosome 6 in diverse tumor types.

Item Type: Paper
Uncontrolled Keywords: Cell Line Chromosome Mapping Chromosomes Human, Pair 6 Genes ras Humans Leukemia genetics Neoplasms genetics Nucleic Acid Hybridization Oncogenes
Subjects: bioinformatics > genomics and proteomics > annotation > map annotation
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > chromosome
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > chromosomes, structure and function > chromosome

bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > genes, structure and function > genes: types > oncogene
CSHL Authors:
Communities: CSHL labs > Wigler lab
Depositing User: CSHL Librarian
Date: July 1987
Date Deposited: 05 Apr 2012 18:25
Last Modified: 24 Feb 2017 21:44
URI: http://repository.cshl.edu/id/eprint/26019

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