Neural prosthetic control signals from plan activity

Shenoy, K. V., Meeker, D., Cao, S., Kureshi, S. A., Pesaran, B., Buneo, C. A., Batista, A. P., Mitra, P. P., Burdick, J. W., Andersen, R. A. (2003) Neural prosthetic control signals from plan activity. NeuroReport, 14 (4). pp. 591-596. ISSN 09594965 (ISSN)

URL: https://www.ncbi.nlm.nih.gov/pubmed/12657892
DOI: 10.1097/00001756-200303240-00013

Abstract

The prospect of assisting disabled patients by translating neural activity from the brain into control signals for prosthetic devices, has flourished in recent years. Current systems rely on neural activity present during natural arm movements. We propose here that neural activity present before or even without natural arm movements can provide an important, and potentially advantageous, source of control signals. To demonstrate how control signals can be derived from such plan activity we performed a computational study with neural activity previously recorded from the posterior parietal cortex of rhesus monkeys planning arm movements. We employed maximum likelihood decoders to estimate movement direction and to drive finite state machines governing when to move. Performance exceeded 90% with as few as 40 neurons. © 2003 Lippincott Williams & Wilkins.

Item Type: Paper
Uncontrolled Keywords: Bayesian decoders Brain computer interfaces Finite state machines Maximum likelihood Neural prosthetic systems Posterior parietal cortex animal experiment arm movement article Bayes theorem body movement brain computer interface machine maximum likelihood method motor control nonhuman parietal lobe planning priority journal prosthesis rhesus monkey Action Potentials Animals Arm Artificial Limbs Databases Factual Macaca mulatta Motor Activity Motor Neurons Numerical Analysis Computer-Assisted Psychomotor Performance Signal Transduction Time Factors
Subjects: bioinformatics > computational biology
organs, tissues, organelles, cell types and functions > tissues types and functions > neural networks
organs, tissues, organelles, cell types and functions > cell types and functions > cell functions > neural plasticity
CSHL Authors:
Communities: CSHL labs > Mitra lab
Depositing User: CSHL Librarian
Date Deposited: 02 Apr 2012 20:28
Last Modified: 06 Feb 2017 17:44
Related URLs:
URI: http://repository.cshl.edu/id/eprint/25882

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