Time to change: retina sends a messenger to promote plasticity in visual cortex

Huang, Z. J., Di Cristo, G. (2008) Time to change: retina sends a messenger to promote plasticity in visual cortex. Neuron, 59 (3). pp. 355-8. ISSN 1097-4199 (Electronic)

URL: https://www.ncbi.nlm.nih.gov/pubmed/18701062
DOI: 10.1016/j.neuron.2008.07.029

Abstract

Maturation of GABA inhibitory circuitry in primary visual cortex activates the critical period of plasticity, but the underlying mechanisms are not well understood. In the August 8th issue of Cell, Sugiyama et al. demonstrate that visual experience promotes the passage of a retina-derived homeoprotein along the visual pathway, which nurtures subclasses of cortical interneurons implicated in regulating critical period plasticity.

Item Type: Paper
Uncontrolled Keywords: Animals Critical Period Psychology Models Biological Neuronal Plasticity physiology Retina physiology Visual Cortex cytology physiology Visual Pathways physiology gamma-Aminobutyric Acid metabolism
Subjects: bioinformatics > genomics and proteomics > small molecules > GABAergic
organs, tissues, organelles, cell types and functions > cell types and functions > cell functions > neural plasticity
organs, tissues, organelles, cell types and functions > tissues types and functions > visual cortex
CSHL Authors:
Communities: CSHL labs > Huang lab
Depositing User: CSHL Librarian
Date Deposited: 10 Apr 2012 18:32
Last Modified: 10 Jan 2017 15:40
Related URLs:
URI: http://repository.cshl.edu/id/eprint/25802

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