PTEN and p53: who will get the upper hand?

Trotman, L. C., Pandolfi, P. P. (February 2003) PTEN and p53: who will get the upper hand? Cancer Cell, 3 (2). pp. 97-9. ISSN 1535-6108 (Print)1535-6108 (Linking)

URL: http://www.ncbi.nlm.nih.gov/pubmed/12620402
DOI: 10.1016/S1535-6108(03)00022-9

Abstract

Mutations of PTEN and p53 are very frequent, yet often mutually exclusive due to functional interdependence of the proteins and, according to a new study, the most intimate possible interaction: direct binding.

Item Type: Paper
Uncontrolled Keywords: Animals Cell Cycle Genes Tumor Suppressor physiology Humans Mice Mice Knockout PTEN Phosphohydrolase Phosphoric Monoester Hydrolases genetics metabolism Signal Transduction Tumor Suppressor Protein p53 genetics metabolism Tumor Suppressor Proteins genetics metabolism
Subjects: bioinformatics > genomics and proteomics > genetics & nucleic acid processing > protein structure, function, modification > protein types > PTEN
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > genes, structure and function > genes: types > p53
CSHL Authors:
Communities: CSHL labs > Trotman lab
Depositing User: Brian Soldo
Date: February 2003
Date Deposited: 23 Mar 2012 16:07
Last Modified: 08 May 2013 16:47
Related URLs:
URI: http://repository.cshl.edu/id/eprint/25523

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