Slicer and the Argonautes

Tolia, N. H., Joshua-Tor, L. (January 2007) Slicer and the Argonautes. Nature Chemical Biology, 3 (1). pp. 36-43. ISSN 1552-4450

URL: http://www.ncbi.nlm.nih.gov/pubmed/17173028
DOI: 10.1038/nchembio848

Abstract

Though they started out as somewhat mysterious components of the RNAi effector complexes, Argonaute proteins have since taken center stage in RNAi gene silencing. They interact with small RNAs to effect gene silencing in all RNAi-related pathways known so far. We will review the dramatic advances in our understanding of the role of the Argonautes in RNAi through studies of their structure and function.

Item Type: Paper
Uncontrolled Keywords: INDUCED SILENCING COMPLEX RNAI EFFECTOR COMPLEXES C-ELEGANS CRYSTAL-STRUCTURE MESSENGER-RNA PAZ DOMAIN SCHIZOSACCHAROMYCES-POMBE HETEROCHROMATIN FORMATION PASSENGER-STRAND UBIQUITIN LIGASE
Subjects: bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > RNAi
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > protein structure, function, modification > protein types > argonaute proteins
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > sRNA
CSHL Authors:
Communities: CSHL labs > Joshua-Tor lab
Watson School > Publications
Depositing User: CSHL Librarian
Date: January 2007
Date Deposited: 03 Nov 2011 14:40
Last Modified: 26 Sep 2014 14:21
Related URLs:
URI: http://repository.cshl.edu/id/eprint/23156

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