It's a small RNA world, after all

Vaughn, M. W., Martienssen, R. (September 2005) It's a small RNA world, after all. Science, 309 (5740). pp. 1525-6. ISSN 1095-9203 (Electronic)

URL: http://www.ncbi.nlm.nih.gov/pubmed/16141062
DOI: 10.1126/science.1117805

Abstract

Small RNAs (sRNAs) can regulate transcript and protein abundance. Previously, they have been identified using traditional cloning approaches, which has limited how many could be characterized. Now, the Meyers and Green laboratories have used massively parallel signature sequencing technology to find over 1.5 million sRNAs in Arabidopsis thaliana. These new sRNAs reveal a greater-than-expected potential role for sRNAs in gene regulation, preferential expression or usage of sRNAs in flowers, and the prospect of targeted sRNA-mediated regulation of pseudogenes. In addition, new plant microRNAs have been identified, some of which may be unique to Arabidopsis.

Item Type: Paper
Uncontrolled Keywords: Arabidopsis genetics metabolism Gene Expression Regulation Plant Genome Plant Genomics MicroRNAs physiology RNA Plant physiology RNA Small Interfering physiology
Subjects: bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > mRNA dynamics
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > siRNA
CSHL Authors:
Communities: CSHL labs > Martienssen lab
Depositing User: CSHL Librarian
Date: 2 September 2005
Date Deposited: 05 Jan 2012 16:10
Last Modified: 09 Apr 2014 20:49
Related URLs:
URI: http://repository.cshl.edu/id/eprint/22726

Actions (login required)

Administrator's edit/view item Administrator's edit/view item
CSHL HomeAbout CSHLResearchEducationNews & FeaturesCampus & Public EventsCareersGiving