RNAi as a bioinformatics consumer

Sachidanandam, Ravi (June 2005) RNAi as a bioinformatics consumer. Brief Bioinform, 6 (2). pp. 146-62. ISSN 1467-5463 (Print)

DOI: 10.1093/bib/6.2.146

Abstract

RNAi has shown great potential for use as a tool for biological discovery, analysis and therapeutics. The involvement of the RNAi pathway in post-transcription silencing, transcriptional silencing and epigenetic silencing as well as its use as a tool for forward genetics and therapeutics throws up several bioinformatics challenges. This paper delineates several areas of research and reviews work that has already been done, the tools that are available and the challenges that lie ahead.

Item Type: Paper
Uncontrolled Keywords: Computational Biology/ methods Gene Targeting/ methods MicroRNAs/ chemistry/ genetics Oligonucleotide Array Sequence Analysis/ methods RNA Interference/ physiology Trans-Activation (Genetics)/ genetics
Subjects: bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > transcription
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > genes, structure and function > gene silencing
CSHL Authors:
Depositing User: CSHL Librarian
Date: June 2005
Date Deposited: 06 Jan 2012 16:51
Last Modified: 06 Jan 2012 16:51
URI: http://repository.cshl.edu/id/eprint/22690

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