A conserved microRNA signal specifies leaf polarity

Timmermans, M. C., Juarez, M. T., Phelps-Durr, T. L. (2004) A conserved microRNA signal specifies leaf polarity. Cold Spring Harb Symp Quant Biol, 69. pp. 409-17. ISSN 0091-7451 (Print)

URL: https://www.ncbi.nlm.nih.gov/pubmed/16117675
DOI: 10.1101/sqb.2004.69.409

Abstract

Plant shoots are characterized by indeterminate growthresulting from the action of a population of stem cells inthe central zone of the shoot apical meristem (SAM) (Fig.1). These stem cells give rise to peripheral derivativesfrom which lateral organs, such as leaves and flowers,arise. Leaves of higher plants exhibit a varying degree ofasymmetry along their adaxial/abaxial (upper/lower)axis. This asymmetry is thought to reflect inherent positional differences in the developing organ relative to theSAM (Wardlaw 1949). The adaxial/dorsal side of the leafdevelops in close proximity to the stem cells in the SAM,whereas the abaxial/ventral side develops at a greater distance from the apex. Evidence that the meristem is required for pattern formation within lateral organs camefrom early surgical experiments in potato (Sussex 1951,1955). Incisions that separate the incipient primordiumfrom the central zone of the SAM resulted in formation ofa radially symmetric abaxialized leaf, suggesting that asignal from the SAM is required to specify adaxial cellfate. The exact nature of this adaxializing signal remainselusive despite the recent identification of several genefamilies required for the determination of adaxial orabaxial identity.

Item Type: Paper
Uncontrolled Keywords: Arabidopsis genetics growth & development metabolism Body Patterning genetics Gene Expression Regulation Developmental Meristem growth & development MicroRNAs biosynthesis genetics Models Biological Plant Leaves growth & development Plants genetics growth & development metabolism RNA Plant biosynthesis genetics Signal Transduction genetics
Subjects: bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > miRNA
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > miRNA
CSHL Authors:
Communities: CSHL labs > Timmermans lab
Depositing User: CSHL Librarian
Date: 2004
Date Deposited: 17 Jan 2012 16:43
Last Modified: 21 Feb 2017 17:42
Related URLs:
URI: http://repository.cshl.edu/id/eprint/22505

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