Maps in the brain: what can we learn from them?

Chklovskii, D. B., Koulakov, A. A. (2004) Maps in the brain: what can we learn from them? Annu Rev Neurosci, 27. pp. 369-92. ISSN 0147-006X (Print)

URL: https://www.ncbi.nlm.nih.gov/pubmed/15217337
DOI: 10.1146/annurev.neuro.27.070203.144226

Abstract

In mammalian visual cortex, neurons are organized according to their functional properties into multiple maps such as retinotopic, ocular dominance, orientation preference, direction of motion, and others. What determines the organization of cortical maps? We argue that cortical maps reflect neuronal connectivity in intracortical circuits. Because connecting distant neurons requires costly wiring (i.e., axons and dendrites), there is an evolutionary pressure to place connected neurons as close to each other as possible. Then, cortical maps may be viewed as solutions that minimize wiring cost for given intracortical connectivity. These solutions can help us in inferring intracortical connectivity and, ultimately, in understanding the function of the visual system.

Item Type: Paper
Uncontrolled Keywords: Animals Axons physiology ultrastructure Brain Mapping Dendrites physiology ultrastructure Humans Nerve Net anatomy & histology growth & development physiology Neural Pathways anatomy & histology growth & development physiology Visual Cortex anatomy & histology growth & development physiology Visual Fields physiology Visual Pathways anatomy & histology growth & development physiology
Subjects: organs, tissues, organelles, cell types and functions > tissues types and functions > visual cortex
CSHL Authors:
Communities: CSHL labs > Koulakov lab
CSHL labs > Chklovskii lab
Depositing User: CSHL Librarian
Date: 2004
Date Deposited: 09 Feb 2012 16:12
Last Modified: 18 Jan 2017 19:50
Related URLs:
URI: http://repository.cshl.edu/id/eprint/22351

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