Behavioral state-dependent reconfiguration of song-related network activity and cholinergic systems

Shea, S. D., Margoliash, D. (2010) Behavioral state-dependent reconfiguration of song-related network activity and cholinergic systems. Journal of Chemical Neuroanatomy, 39 (2). pp. 132-140. ISSN 0891-0618

URL: https://www.ncbi.nlm.nih.gov/pubmed/19853654
DOI: 10.1016/j.jchemneu.2009.10.002

Abstract

The song system of oscine songbirds mediates multiple complex perceptive and productive behaviors. These discrete behaviors are modulated according to external variables such as social context, directed attention and other forms of experience. In addition, sleep has been implicated in song learning and song maintenance. Changes in behavioral state are associated with complex changes in auditory responsiveness and tonic/bursting properties of song system neurons. Cholinergic input, principally from the basal forebrain has been implicated in some of these state-dependent properties. Cholinergic modulation may affect numerous song system nuclei, with in vivo and in vitro studies indicating that a major target of cholinergic input is the forebrain nucleus HVC. Within HVC, a muscarinic cholinergic system has strong regulatory effects on most neurons, and may serve to couple and uncouple circuitry within HVC projecting along the premotor pathway with circuitry within HVC projecting along the cortico-basal ganglia pathway. These observations begin to describe how neuromodulatory regulation in the song system may contribute to learning phenomena. (C) 2009 Elsevier B.V. All rights reserved.

Item Type: Paper
Uncontrolled Keywords: Acetylcholine Cholinergic regulation Bird song system HVC BASAL FOREBRAIN NEURONS MALE ZEBRA FINCHES LEARNED VOCAL COMMUNICATION IDENTIFIED HVC NEURONS WHITE-CROWNED SPARROW NUCLEUS BASALIS AUDITORY RESPONSES ANESTHETIZED RATS MOTOR SYSTEM MUSCARINIC RECEPTORS
Subjects: organism description > animal behavior
organism description > animal > bird
organs, tissues, organelles, cell types and functions > cell types and functions > cell types > neurons
organs, tissues, organelles, cell types and functions > cell types and functions > cell types > neurons
organs, tissues, organelles, cell types and functions > cell types and functions > cell types > neurons

organism description > animal > mammal > rodent > rat
organism description > animal > mammal > rodent > rat
CSHL Authors:
Communities: CSHL labs > Shea lab
Depositing User: CSHL Librarian
Date Deposited: 19 Oct 2011 14:54
Last Modified: 10 Feb 2017 22:02
PMCID: PMC2822057
Related URLs:
URI: http://repository.cshl.edu/id/eprint/15526

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