The auditory cortex mediates the perceptual effects of acoustic temporal expectation

Jaramillo, E. S., Zador, A. M. (2010) The auditory cortex mediates the perceptual effects of acoustic temporal expectation. Nat Neurosci, 14 (2). pp. 246-51. ISSN 1546-1726 (Electronic) 1097-6256 (Linking)

URL: http://www.ncbi.nlm.nih.gov/pubmed/21170056
DOI: 10.1038/nn.2688

Abstract

When events occur at predictable instants, anticipation improves performance. Knowledge of event timing modulates motor circuits and thereby improves response speed. By contrast, the neuronal mechanisms that underlie changes in sensory perception resulting from expectation are not well understood. We developed a behavioral procedure for rats in which we manipulated expectations about sound timing. Valid expectations improved both the speed and the accuracy of the subjects' performance, indicating not only improved motor preparedness but also enhanced perception. Single-neuron recordings in primary auditory cortex showed enhanced representation of sounds during periods of heightened expectation. Furthermore, we found that activity in auditory cortex was causally linked to the performance of the task and that changes in the neuronal representation of sounds predicted performance on a trial-by-trial basis. Our results indicate that changes in neuronal representation as early as primary sensory cortex mediate the perceptual advantage conferred by temporal expectation.

Item Type: Paper
Subjects: organs, tissues, organelles, cell types and functions > cell types and functions > cell types > neurons
organs, tissues, organelles, cell types and functions > cell types and functions > cell types > neurons
organs, tissues, organelles, cell types and functions > cell types and functions > cell types > neurons

organism description > animal > mammal > rodent > rat
organism description > animal > mammal > rodent > rat
CSHL Authors:
Communities: CSHL labs > Zador lab
CSHL Post Doctoral Fellows
Depositing User: CSHL Librarian
Date Deposited: 03 Oct 2011 13:31
Last Modified: 02 May 2013 18:51
PMCID: PMC3152437
Related URLs:
URI: http://repository.cshl.edu/id/eprint/15440

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