Small RNAs are on the move

Chitwood, D. H., Timmermans, M. C. P. (September 2010) Small RNAs are on the move. Nature, 467 (7314). pp. 415-419. ISSN 0028-0836

URL: http://www.ncbi.nlm.nih.gov/pubmed/20864994
DOI: 10.1038/nature09351

Abstract

A key feature of RNA interference is its ability to spread from cell to cell. Such non-cell-autonomous gene silencing has been characterized extensively in both plants and animals, but the identity of the mobile silencing signal has remained elusive. Several recent studies now shed light on the identity of this signal in plants, and indicate that small RNA molecules-from short-interfering RNAs to microRNAs-are capable of moving between cells and through the vasculature. The movement of small, 21-24-nucleotide RNA species has implications for biological processes ranging from developmental patterning and stress responses to epigenetic inheritance.

Item Type: Paper
Uncontrolled Keywords: SILENCING SIGNAL ARABIDOPSIS GENE INTERFERENCE MICRORNAS CELLS PATHWAYS SIRNAS PLANTS VIRUS
Subjects: organism description > plant > Arabidopsis
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > RNAi
organism description > plant
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > shRNA
organism description > virus
CSHL Authors:
Communities: CSHL labs > Timmermans lab
Watson School > Publications
Depositing User: CSHL Librarian
Date: 23 September 2010
Date Deposited: 28 Sep 2011 15:02
Last Modified: 26 Sep 2014 19:41
Related URLs:
URI: http://repository.cshl.edu/id/eprint/15387

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