A method for detection and classification of events in neural activity

Bokil, H. S., Pesaran, B., Andersen, R. A., Mitra, P. P. (2006) A method for detection and classification of events in neural activity. IEEE Trans Biomed Eng, 53 (8). pp. 1678-87. ISSN 0018-9294 (Print)

URL: https://www.ncbi.nlm.nih.gov/pubmed/16916103
DOI: 10.1109/TBME.2006.877802

Abstract

We present a method for the real time prediction of punctuate events in neural activity, based on the time-frequency spectrum of the signal, applicable both to continuous processes like local field potentials (LFPs) as well as to spike trains. We test it on recordings of LFP and spiking activity acquired previously from the lateral intraparietal area (LIP) of macaque monkeys performing a memory-saccade task. In contrast to earlier work, where trials with known start times were classified, our method detects and classifies trials directly from the data. It provides a means to quantitatively compare and contrast the content of LFP signals and spike trains: we find that the detector performance based on the LFP matches the performance based on spike rates. The method should find application in the development of neural prosthetics based on the LFP signal. Our approach uses a new feature vector, which we call the 2d cepstrum.

Item Type: Paper
Uncontrolled Keywords: Algorithms Animals Artificial Intelligence Cluster Analysis Computer Simulation Electroencephalography/ methods Evoked Potentials, Visual/ physiology Macaca Memory/ physiology Models, Neurological Models, Statistical Parietal Lobe/ physiology Pattern Recognition, Automated/ methods Saccades/ physiology
Subjects: bioinformatics > quantitative biology
organs, tissues, organelles, cell types and functions > cell types and functions > cell types > neurons
organs, tissues, organelles, cell types and functions > cell types and functions > cell types > neurons
organs, tissues, organelles, cell types and functions > cell types and functions > cell types > neurons

organism description > animal > mammal > primates
CSHL Authors:
Communities: CSHL labs > Mitra lab
Depositing User: CSHL Librarian
Date Deposited: 29 Aug 2011 20:17
Last Modified: 06 Feb 2017 17:02
Related URLs:
URI: http://repository.cshl.edu/id/eprint/14860

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